WGU Advanced Pathophysiology ( D115) exam latest (PCC2)

A pediatric patient is showing signs of failure to thrive. An advanced practice registered nurse (APRN) also notices the patient does not focus on objects. The parent is concerned about their child’s uncoordinated movement. Which diagnosis should the APRN pursue?

A. Lafora disease

B. Lesch-Nyhan syndrome

C. Rett syndrome

D. Tay-Sachs disease

A couple experiences a miscarriage at 10 weeks. Genetic analysis reveals trisomy 16. In a later pregnancy, a child is born with mosaic trisomy 16. What explains the survival of the second pregnancy?

A. Partial trisomy

B. Loss of extra chromosome

C. Chromosomal mosaicism

D. Maternal factors

A patient tests positive for COVID-19 and reports mild symptoms compared to a prior severe infection. Which immunologic mechanism explains this?

A. Rapid IgG production from memory B cells

B. Innate immune activation

C. Passive immunity

D. IgM production

An infant has not yet received MMR vaccine and is at risk during an outbreak. What explains protection and management?

A. Herd immunity prevents all transmission

B. Immune system too immature

C. Waning maternal antibodies; early vaccination possible

D. Fully protected by maternal antibodies

Which lifestyle recommendation reduces cancer risk?

A. Mediterranean diet

B. Alcohol up to 50 g/day

C. BMI less than 29.9

D. 1 hour exercise weekly

Which is the most common congenital malformation?

A. Hydrocephaly

B. Pyloric stenosis

C. Clubfoot

D. Heart defects

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